Role of the uterus in human reproduction:

Reproduction is the most important phenomena in all living being for the survival of the generation. The uterus is a very crucial reproductive organ in a human female. After the formation of an egg and its fertilization, it implants the zygote in the uterus where it develops and gets its nutrition until the birth of the baby. Even before the conception of the zygote, uterus secretes some hormones (for example estrogen) which are very crucial to the maturation of the egg. That’s why if a uterus gets infected or damaged because of a disease, it will destroy the whole reproductive cycle and affect the reproduction process.

Why is the uterine transplant needed?

If the uterus or womb of a female gets defected or diseased, she cannot conceive an embryo and give birth to a child thus will be infertile. Sometimes uterine infections also affect the process of reproduction. Proper medications and anti-biotic drugs can cure some infections. But some diseases affect the womb to such a high level that it can’t cure completely; ultimately, the female gets infertile. It is termed as ‘Absolute Uterine Factor Infertility’ (AUIF).

 In such cases, the gynaecologists often recommend the option for the transplant of the uterus. And it also leaves the patient with no option other than the uterine transplantation. The surgical way of replacing a damaged uterus with a healthier one is called the process of uterus transplantation. We can transplant a healthy uterus in place of the diseased one. But this may not be favourable because of several complications that happen during this critical surgery.

What happens when a uterus has to transplant?

Transplant of the uterus is the last option for a female to get fertile again. But this is perilous. There is the chance of several other disorders and complication because this organ is difficult to transplant as the whole system is very sensitive. Let us tell you what happens when a doctor tries to transplant a womb. Following are the major risks of uterine transplantation:

  • The donor, whose healthy uterus is removed, is also subject to many complications.
  • A female with a removed uterus is subject to many infections and abnormalities in the menstrual cycle.
  • The recipient is also at risk of transplant rejection.
  • If the tissues of the recipient don’t match with the donor’s tissues, it will create serious issues, and ultimately the transplant would reject
  • Sometimes during the procedure of uterine transplant, some infections may hit the body of the recipient that makes her sick.
  • Even a little mistake in the transplant procedure can pose several threats to the recipient. A wrong transplant will not only make the woman deprived of her reproductive system but also cause many disorders because of too much loss of blood and other risk factors.

All these factors prove that the uterine transplantation is more of a loss than a gain. That’s why this procedure almost cannot treat an infertile female this way.

They report it that in the world’s history, only one woman had a successful uterus transplant and all other patients faced serious issues arising during this complicated process.

The work of Gynecologists for uterine transplant:

The transplant of the uterus to treat the infertility of a female is not a better option because of more risk factors and losses than the gains and benefits of this process. In most cases, the Gynecologists avoid doing this complicated and risky surgery. And the statistics show that there is a very less number of total women who had operated for a uterine transplant, only less than 20 women in the world had undergone this surgery. Doctors and medical researchers in many countries are still working on it. They are working to devise some better techniques for uterine transplantation so that its complications can lessen to some extent. Some drugs can make it easy or practical to some extent for the augmentation of the surgical treatments of the defected uterus. 

Other treatment options for infertility:

Medical professionals are taking into consideration the failure of the procedure of uterus transplantation because of complications. They are trying to suggest some better ways to treat the absolute uterine factor infertility. The National Women’s Health Network, which is working for the solution of female diseases, has pointed to many other options for the cure of infertility because of the defective uterus. These treatment options include various kinds of medications and anti-biotic and healing drugs, which can improve the condition of an infected uterus to a beneficial level. But still, there is a need to introduce even more effective ways to treat this serious issue. The first US Uterus transplant, the complications were unspecified. The operation took place in Ohio. It was a highly experimental procedure.


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